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Clinical and pathophysiological aspects of intrahepatic cholestasis of pregnancy
(2012-11-20)
Objective: The pathogenesis of intrahepatic cholestasis of pregnancy (ICP) involves impaired bile acid and estrogen/progesterone metabolism and excretion based on genetic and environmental factors. In this thesis we evaluated ...
Factors affecting attendance at population-based mammography screening
(2002-01-11)
The aim of the studies described in this thesis was to explore factors affecting attendance at outreach mammography screening, and to assess possible associations between socioeconomic factors and breast cancer ...
Involvement of lipid rafts in G protein-coupled monoamine receptor trafficking and signaling : a pharmacological approach
(2008-04-25)
The present work focused on lipid raft-mediated modulation of signaling
and trafficking of serotonin (5-HT) and dopamine receptors. The 5-HT
system is one of the most complex neurotransmitter systems, with a wide
distribution ...
Diabetes, metformin and gastric adenocarcinoma
(2021-05-18)
Diabetes may increase the risk and mortality of certain cancers, but its association with gastric adenocarcinoma is not clear. On the other hand, metformin, a first-line treatment for diabetes, may reduce cancer risks and ...