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Children's testimony
(2002-11-26)
Background: Most cases of child sexual use are identified through statements made by children and in many cases such statements constitute the only evidence available that abuse occurred. Despite its importance the use of ...
Socioeconomic differences in alcohol habits, alcohol-related disorders and mortality
(2016-10-27)
The overall aim of this thesis is to enhance knowledge about stability and predictors of change in alcohol habits among different sociodemographic subgroups, and to assess the contribution of alcohol use to social differences ...
Epidemiological studies of epilepsy : incidence and risk factors
(2011-10-28)
Epilepsy is one of the most common serious neurological disorders leading to significant consequences for the affected. Despite the wealth of epidemiological data, there are still many un-answered questions. The major ...
Thioredoxin-1 in Alzheimer disease
(2015-11-05)
Oxidative stress is one of the earliest signs in Alzheimer Disease (AD) brain. In order to protect themselves against oxidative stress, neurons use antioxidants as a defense mechanism. Such an antioxidant is Thioredoxin-1 ...
Regulation of human thioredoxin and glutaredoxin systems by oxidation and S-nitrosylation
(2008-03-21)
The homeostasis of intracellular redox status has a crucial role in the
cell survival and different processes such as DNA synthesis, gene
expression, enzymatic activity, etc. This homeostasis is achieved via an
intense ...
Role of thioredoxin system in cell death caused by toxic compounds
(2014-02-17)
Thioredoxin systems, comprising Trx, TrxR and NADPH, are one of the major disulfide reductase systems, which is crucial in maintaining cellular redox balance in mammalian cells. TrxR is a selenoprotein with a Sec residue ...
A register-based study of health equity in Swedish stroke and diabetes care delivery
(2019-01-18)
Stroke and diabetes are relatively common conditions and have a huge impact on society’s burden of illness; over 400 million people around the world live with diabetes and 15 million have a stroke every year. Estimates on ...