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Changes in mitogen-activated protein kinase phosphorylation and inorganic phosphate induced by skeletal muscle contraction
(2002-10-04)
Skeletal muscles adjust to the level of contractile activity by different biochemical alterations. Contraction is a multifactorial stimulus with short-term metabolic effects and long-term responses due to changes in protein ...
Serine / threonine protein phosphatase 5 – a double-edged sword : in the progression towards diabetes
(2012-05-15)
Type 2 diabetes mellitus is increasing at an alarming rate worldwide. In the development and progression of type 2 diabetes mellitus, the insulin-producing pancreatic β-cells are commonly exposed to a hyperglycemic and ...
Diabetogenic effects of glucocorticoids : role of protein phosphatase 5 and GLP-1 receptor activation
(2014-02-28)
Obesity, the metabolic syndrome and type 2 diabetes are inextricably linked together, and all increase with rapid pace globally. Glucocorticoid (GC) excess is associated with diabetogenic effects, including insulin resistance ...