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Diabetogenic effects of glucocorticoids : role of protein phosphatase 5 and GLP-1 receptor activation
(2014-02-28)
Obesity, the metabolic syndrome and type 2 diabetes are inextricably linked together, and all increase with rapid pace globally. Glucocorticoid (GC) excess is associated with diabetogenic effects, including insulin resistance ...
Factors in the environment, viruses and host responses affecting the epidemiology of tick-borne encephalitis virus in Northern Europe
(2014-08-26)
Tick-borne encephalitis virus (TBEV) circulates mainly in the Ixodes ricinus and Ixodes persulcatus tick species, which serve both as hosts and vectors for the virus. Wild rodents are considered as bridges for non-viremic ...
Modelling and calculation of DNA damage and repair in mammalian cells induced by ionizing radiation of different quality
(2013-05-21)
Recent experimental data have revealed a wealth of information that provides an exceptional opportunity to construct a mechanistic model of DNA repair. The cellular response to radiation exposure starts with repair of DNA ...
Airborne occupational exposures and risk of developing rheumatoid arthritis
(2019-05-24)
Background: Rheumatoid Arthritis (RA) is an autoimmune, inflammatory disease with multifaceted aetiology. Cigarette smoke is the strongest environmental risk factor of RA, and research suggests that airborne exposures may ...