Search
Now showing items 1-10 of 20
Puumala hantavirus : immune responses and vaccines
(2002-05-10)
Hantaviruses (family Bunyaviridae) is a group of closely related zoonotic rodent-borne viruses that are transmitted to humans through inhalation of infected rodent excreta. They cause hemorrhagic fever with renal syndrome ...
Platelet dysfunction in diabetes mellitus : impact of hyperglycemia and glycoprotein GPIIb/IIIa inhibition
(2009-02-06)
Diabetes mellitus (DM) is associated with increased cardiovascular
morbidity and mortality, due to diabetic angiopathy. Hyperglycemia is one
of the factors that may cause platelet dysfunction in diabetic patients.
This ...
Psoriasis : studies of phenotype at onset and of associated cardiovascular morbidity
(2005-08-12)
Psoriasis is a complex inflammatory skin disorder, affecting 2-3% of the population in the western world. The etiology of psoriasis is not yet known. However it is likely that its pathogenesis involves interplay between ...
Clinical and genetic stratification of childhood psoriasis
(2015-04-29)
Psoriasis is a clinically heterogeneous and common disease affecting about 2-3% of the
population in Sweden. Twin and family studies have shown a strong and complex genetic
background in psoriasis. The strongest known ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
Psoriasis is a common and chronic skin disease with multifactorial background. It affects approximately 2% of the Swedish population and is characterized by inflammatory and scaly lesions. The aetiology of psoriasis is not ...
The rheumatoid forefoot : surgical treatment and epidemiological aspects
(2007-01-12)
Background: The forefoot is frequently involved in rheumatoid arthritis
(RA) resulting in a painful, handicapping deformity. The prevalence
stated has long been based on a study from 1956. The most common surgical
treatment ...
Drug utilization in children with asthma : methodological approaches and practical implications
(2019-02-12)
There is limited research on drug utilization among children, despite them representing 20% of the total population in Europe. In the Priority Medicines report, the World Health Organization suggested that drug utilization ...
Investigation of T cell driven arthritis induced by mannan in ZAP70 mutated SKG mice
(2016-08-10)
Autoimmune diseases are particularly challenging to study in human due to their complex multifactorial nature. In rheumatoid arthritis (RA), self-reactivity directed against joints leads to pain, tissue destruction and ...
Studies on the gamma-secretase complex and processing of the Alzheimer's disease-associated amyloid precursor protein
(2004-03-26)
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that
causes the most common form of dementia. Pathological lesions, such as
plaques consisting of the amyloid beta-peptide (Ab), are found in the
brains ...
Large organic aerosols in a human exposure chamber : applications in occupational dermatology and lung medicine
(2006-04-03)
Exposure to large organic aerosol particles may cause respiratory and skin reactions. The use of human exposure chambers offers possibilities for experimental exposure challenges carried out with patients, in research and ...