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Chromatin remodelling and gene regulation
(2001-04-06)
Chromatin plays an important role in gene regulation, as it forms an obstacle for a number of proteins that need access to the DNA. Several protein complexes that open up the chromatin structure have been identified and ...
The impact of lifestyles on the occurrence of dementia
(2001-05-09)
This thesis explored the impact of different lifestyles in late life on the occurrence of Alzheimer's disease (AD) or dementia. Smoking, vitamin B12 and folate in relation to AD have been extensively studied, but the results ...
District nurses' experiences of wound care in primary health care : management and knowledge
(2012-11-05)
Aim: The overall aim of this thesis was to deepen the knowledge of wound management in primary healthcare from district nurses' (DNs) perspective. The thesis includes one pilot study (I) and two qualitative studies (II, ...
Life situation, information needs, and information seeking in patients with oesophageal cancer and their family members
(2006-10-06)
This thesis explores the experiences of living with oesophageal cancer from the perspective of patients and family members. Also, their needs for information and how they seek information in relation to the illness were ...
Collaboration and knowledge development in wound management : experiences from different professional perspectives in primary healthcare and education
(2017-02-20)
Aim: The overall aim of this thesis is to explore collaboration and knowledge development in wound management in practice and in education. One specific aim is to investigate district nurses’ (DNs’) wound management according ...
Discovery and validation of prognostic markers for cutaneous melanoma
(2018-04-13)
During the last years there has been an alarming increase in incidence of cutaneous melanoma (CMM) which is the deadliest form of skin cancer. There has been a paradigm shift in treatment of disseminated stage IV disease ...
Studies of the role of the cathelicidin peptide LL-37 in epithelial biology
(2010-05-14)
The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, ...
HIV-1 genotype and vertical transmission in northern Vietnam
(2008-10-28)
After 18 years from the beginning of the HIV-1/AIDS epidemic in Vietnam, the number of HIV-1 infected individuals is still increasing. Investigations conducted at two distinct time points in two separate groups of HIV-1 ...
Developing working conditions
(2011-04-08)
The overall aim of this thesis was to investigate working conditions and organizational strategies providing conditions for job resources with potential for development, positive well-being and health. The aim was formed ...
Metabolism and neural differentiation in childhood neuroblastoma
(2017-05-19)
Neuroblastoma is the most common and aggressive extracranial solid tumor during childhood. MYCN-amplification is found in approximately 25 % of all neuroblastoma cases, and is defined as high-risk disease. Development of ...