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Re-establishing reading skills of elderly low vision patients : studies on Swedish low vision clinic clients
(2000-11-17)
This thesis is based on the project "Reading skills, reading training and technology for the visually handicapped - Prospects for the 1990s," carried out at the Department of Educational Research of the Stockholm Institute ...
Long-term clinical, histological and virological outcomes after sustained virologic response in patients with chronic hepatitis C
(2017-05-09)
Successful antiviral treatment of chronic hepatitis C (HCV), resulting in Sustained Virologic Response (SVR) has been shown to reduce the risk for liver related complications, hepatocellular carcinoma (HCC) and death. ...
Side-chain oxidized oxysterols as metabolic regulators in liver and brain
(2014-02-03)
Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion ...
Effect of pharmacological treatment of serotonergic function in depression
(2002-05-03)
Since its identification in raphe neurons of the central nervous system (CNS), the biogenic amine serotonin (5- hydroxytryptamin, 5-HT) has been implicated in the etiology and pathophysiology of affective disorders, such ...
The role of interferon-regulated genes in the immune system
(2017-01-25)
Type I interferons (IFNs) are potent inducers of the first-line defense against pathogens. Their activity leads to the up- and downregulation of a large number of genes with various effects on the immune system, including ...
Impairment of B cell trafficking and differentiation during HIV-1 infection
(2011-10-05)
During the course of HIV-1 infection, several B cell dysfunctions occur as result of virus replication and indirect mechanisms of immunopathology. The B cells abnormalities include hypergammaglobulinemia, a decreased number ...
The risk of type 1 diabetes in immigrants and their offspring in Sweden : the influence of perinatal factors
(2014-11-13)
Aims: The overall aim of this study was to investigate the trend in and risk factors for type 1 diabetes, with particular reference to parental socioeconomic position (SEP) and country of birth of subjects and their parents. ...
Low back pain among industrial workers : occupational health studies on prevalence, incidence, and associations with work and lifestyle in I.R. Iran
(2007-02-23)
This thesis presents the results from a prospective industrial population
cohort study on epidemiology and risk factors for low back pain (LBP) in
Iran. The four papers in the thesis were based on a cross-sectional
survey ...
Pharmacokinetics and inner ear transport of cisplatin
(2015-02-25)
Background: Cisplatin is a commonly used platinum anti-cancer drug. Regrettably cisplatin
has dose-limiting ototoxic side effects, e.g. the drug can induce an irreversible
hearing loss. The ototoxic mechanisms of cisplatin ...
Bilateral prophylactic mastectomy and immediate breast reconstruction with implants
(2009-11-20)
Bilateral prophylactic mastectomy (BPM) followed by immediate breast reconstruction (IBR) has been more frequently performed over the last 10 years to prevent breast cancer in high-risk women. Since this procedure is ...