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The role of interferon-regulated genes in the immune system
(2017-01-25)
Type I interferons (IFNs) are potent inducers of the first-line defense against pathogens. Their activity leads to the up- and downregulation of a large number of genes with various effects on the immune system, including ...
Factors associated with lung function impairment in children and adults with obstructive lung disease
(2008-05-14)
Obstructive lung diseases are a group of diseases in which there is a limitation in the flow of air into or out of the lungs. Two common such diseases are asthma, which is found in both children and adults, and chronic ...
Exosomes in immune regulation and allergy
(2007-04-20)
Exosomes are nano-sized vesicles of endosomal origin which are secreted from several different cell types. Depending on their cellular source they have been suggested to have different functions, like having a role in ...
Studies on the role of SOCS3 and STAT3 in development and function of the immune system
(2017-11-27)
The immune system is composed of an innate and an adaptive response that protects us from the microbial attacks. The innate system provides a fast defense against infection. However, many microbes evade or overwhelm the ...
Mild traumatic brain injury : antecedents and aftermath
(2019-03-08)
Mild Traumatic Brain Injury (mTBI) is a frequent, trauma-induced injury, associated with loss of consciousness and/or memory loss for the injury event. Injured individuals experience a wide range of somatic symptoms (e.g. ...