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Transcriptional regulation of ribosomal RNA gene : actin, myosin and beyond
(2014-05-22)
In the eukaryotic cell nucleus, actin and nuclear myosin 1c (NM1) are key regulators of RNA
polymerase I (Pol I) transcription and function across the entire ribosomal RNA biogenesis
pathway. At the gene level, actin ...
Antiretroviral drug resistant HIV-1 in women and children living in Honduras
(2013-02-15)
Antiretroviral therapy (ART) in HIV infected pregnant women contributes to the prevention of HIV transmission to the newborn. However, as ART can also induce HIV drug resistance during suboptimal levels of virological ...
Ultra-deep characterization of viral quasispecies in HIV infection
(2012-05-22)
HIV-1 has the ability to rapidly diversify and adapt to changes in its environment, such as evading the host immune response, altering cell tropism, and developing resistance to antiretroviral drugs. Minority HIV-1 variants ...