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Lipid-related genes and their associations with coronary heart disease
(2014-04-25)
Coronary heart disease (CHD) is a complex disease caused by the long-term progression of atherosclerosis. Lipids, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and ...
Studies on antidepressant-mediated regulation of signal transduction
(2009-09-07)
Depression affects around 16% of the population at some point in their lives and major depressive disorder is a leading cause of disability worldwide. Depression is caused by an interaction of genetic and environmental ...
Long-term survival and survivorship in non-Hodgkin lymphoma patients in Sweden
(2020-12-11)
Non-Hodgkin lymphoma (NHL) is one of the top ten most common cancer types in Sweden. Although sometimes referred to as one disease, NHL is truly an umbrella term representing a heterogeneous group of diseases with varying ...
Intrinsic brain activity in health and disease
(2015-08-20)
The main part of the brain’s energy need is to support housekeeping functions and internal
information processing, regardless of external tasks. Cognitive brain imaging, aimed at relating
mental phenomena to neurophysiological ...
Targeted therapy in chronic lymphocytic leukemia
(2020-04-28)
Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of mature B lymphocytes in blood, bone marrow and lymphoid tissues. Historically, patients with TP53 aberration and with refractoriness to chemoimmunotherapy ...
Physical workload and exit from the labour market : epidemiological studies with a focus on employees with musculoskeletal disorders
(2022-10-28)
Background: The length of working life is expanding in the light of the ageing population. In response, countries including Sweden are increasing the retirement age. However, many workers, especially workers with heavy ...
Identification of autoantigens in multiple sclerosis
(2023-01-04)
Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system in which cells from primarily the adaptive immune system infiltrate the brain and spinal cord, leading to inflammation and demyelination. ...