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TRIM21/ Ro52 in B cell pathology
(2013-01-25)
Primary Sjögren’s syndrome (pSS) is a systemic autoimmune disease affecting 0.2% of the population. Several B cell aberrances have been linked to pSS, such as autoantibody production, hypergammaglobulinemia and B cell ...
MicroRNA expression and function in virus-associated human cancers
(2013-12-13)
microRNAs (miRNAs) are small non-coding RNAs that play important roles in gene regulation. It is now clear that miRNAs participate in tumor development and progression. Despite many studies have reported specific miRNA ...
Mechanisms of cancer cell death by mutant p53-reactivating compound APR-246
(2021-02-11)
Tumor suppressor TP53 is the most frequently mutated gene in cancer. A majority of TP53 mutations result in a mutant p53 that disrupts its DNA binding capabilities but may also acquire novel gain-of-function activities ...
Risk factors for prostate cancer : analysis of primary data, pooling, and related methodological aspects
(2015-11-18)
Prostate cancer is the second most common cancer among men worldwide, yet its etiology remains
poorly understood. Obesity, on the other hand, is a prevalent but preventable medical condition that is
associated with ...