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MicroRNAs : significance for sensitivity/resistance of lung cancer cells to treatment
(2013-01-24)
Intrinsic or acquired resistance of lung cancer (LC) to chemo- or radiotherapy (CT/RT) limits the treatment effectiveness, which, in turn contributes to tumor progression and ultimately increases the mortality rate of the ...
Cellular immunity and inflammation in atherosclerosis
(2001-11-09)
Atherosclerosis, the major cause of death and disability in western countries, is nowadays recognized as an inflammatory disease. Low density lipoprotein (LDL), the major carrier of cholesterol in plasma, is trapped in the ...
Alzheimer disease associated Abeta and gamma-secretase : mitochondrial localization and involvement in cell death
(2009-01-30)
In several neurodegenerative disorders, including Alzheimer disease (AD)
and Parkinson disease (PD), protein aggregation is accompanied by
mitochondrial dysfunction. An increasing number of proteins found in
mitochondria ...
Umbilical cord blood transplantation : clinical outcome, chimerism development, and in vitro expansion of T-cells for clinical use
(2014-11-21)
Umbilical cord blood (UCB) is an alternative graft source in allogeneic hematopoietic stem cell transplantation (HSCT). The unique advantages with UCB as a stem cell source are found in the permissibility for human leukocyte ...