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Mesenchymal stromal/stem cells : expansion, engraftment and immune modulation
(2009-04-07)
Due to their production of hematopoietic growth factors and their
immunomodulatory capacity, bone marrow-derived mesenchymal stromal/stem
cells (MSC), are a promising tool in the procedure of hematopoietic stem
cell ...
Studies of the device perfect capsule in an animal model to reduce lens epithelial cell proliferation
(2008-09-12)
The sealed-capsule irrigation device, the Perfect Capsule, is a surgical
device designed to target lens epithelial cells (LECs) during cataract
surgery and prevent posterior capsule opacification (PCO). This is
especially ...
Autocrine/paracrine interactions moendocrine pancreasdulating hormone release in the endocrine pancreas
(2007-11-07)
Human islet transplantation is emerging as an alternative to pancreas transplantation or insulin therapy in the treatment of type I diabetes. It has been possible to achieve euglycemia by transplanting isolated human islets ...
Fluoride and health : epidemiological studies of fluoride exposure and hip fracture, myocardial infarction and osteosarcoma
(2016-10-07)
The aim of this thesis was to investigate the association between drinking water fluoride exposure and risk of hip fracture, myocardial infarction, and osteosarcoma. Swedish nation- wide population-based registers have ...
A study of the transition from premalignancy to clinical prostate cancer
(2005-09-16)
Prostate cancer remains the most commonly diagnosed life-threatening malignancy and the second leading cause of death from cancer in men. However, little is known about molecular mechanisms that underline its initiation ...
Biosynthesis of leukotriene B4 in hematological malignancies
(2005-05-27)
Leukotrienes (LT) are biologically active metabolites of the fatty acid
arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA
2), this fatty acid can be converted to leukotrienes, lipoxins,
prostaglandins ...
Morphology and biochemistry of the tympanic membrane in relation to retraction pathology
(2010-03-10)
Otitis media is very common during childhood and may predispose for tympanic membrane (TM) pathology later in life. Therefore, it is important to investigate the possible changes in TMs subjected to otitis media.
There ...
Human parvovirus B19 : studies on the pathogenesis of infection
(2001-05-11)
Human parvovirus B19 (B19) causes the common childhood disease erythema infectiosum. The virus is transmitted by the respiratory route, infects erythroid progenitor cells, and thereby inhibits erythropoiesis. The seroprevalence ...
Estrogen and aryl hydrocarbon receptor signaling
(2009-05-22)
The biological effects of estrogens are mediated by the two estrogen receptor (ER) isoforms, ERa and ERb. The ERs are ligand-inducible transcription factors that belong to the nuclear receptor (NR) superfamily. Ligand-activated ...