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Deuterium-L-DOPA : a novel means to improve treatment of Parkinson's disease
(2012-08-31)
L-DOPA, the precursor of dopamine, is administered to restore dopamine deficiency in Parkinson´s disease (PD) patients. L-DOPA initially provides a sustained symptomatic relief with superior efficacy as compared to other ...
Psychopathic personality in adolescence : genetic and environmental influences
(2009-09-04)
Psychopathy, or psychopathic personality, is a personality disorder characterized by a constellation of deviant interpersonal, affective, and behavioral dimensions. It has consistently been shown that the psychopathic ...
Selection of the principal cause of death : studies on the basis of mortality statistics for rheumatoid arthritis
(1985-02-12)
The official statistics of Sweden for 1971-75 show a 2.7-fold increase in mortality for men and a 3.0-fold increase for women attributed to rheumatoid arthritis (RA) as the underlying cause of death. In order to investigate ...
Tobacco and multiple sclerosis susceptibility
(2016-01-28)
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system (CNS) that arises from a combination of a complex genetic predisposition and environmental factors. For northern Europeans, the ...
Violent crime : addressing causation with family-based methods
(2012-05-15)
Violent crime is an important public health problem, and incurs major costs for society. The effect of interventions has so far been modest, often attributed to a research focus on risk factors for crime, but a relative ...
Regulation of B cell responses to modified self
(2013-10-25)
The immune system needs to be efficient to protect organisms from invading pathogens. Lymphoid organs such as the spleen and lymph nodes are needed to initiate the response. The spleen is important for systemic immunity ...
To unite or disconnect : AmotL2 in tubulogenesis and tumor invasion
(2015-01-16)
For an epithelial- or endothelial cell sheet or ‐tissue to form, individual cells must come together unite and connect. Contacts to adjacent cells and underlying matrix must be initiated, and the junctional proteins mediating ...