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Celiac disease : complications and the role of infection in pathogenesis
(2012-04-17)
Celiac disease (CD) affects about 1% of the Western population. Individuals with CD suffer increased risk of a number of comorbid conditions, including certain malignancies and diabetes mellitus type 1. The pathogenesis ...
Evaluation of medical and/or surgical treatment of anosmia/hyposmia in association with inflammatory disease of the upper airway
(2004-05-21)
Background: There is a lack of evidence-based, prospective studies in treatment of nasal polyposis. The correlations between symptoms, polyp scores and computed tomography (CT) scans have not been studied sufficiently. ...
Roles of NUDT5 and NUDT15 beyond oxidized nucleotide sanitation and their potential as therapeutic targets
(2018-03-15)
The nucleotide precursor pool is readily susceptible to numerous sources of modification and damage, including alkylation, deamination and oxidation/nitrosylation, among others; most of which have deleterious effects on ...