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Matrix metalloproteases and cell motility in malignant mesothelioma
(2004-10-29)
Invasion and metastasis of malignant tumor cells requires destruction of and migration through extracellular matrix (ECM) such as basement membrane and interstitial stroma. The ECM-degrading proteases produced by tumor ...
The TRIM21/Ro52 E3 ligase and its antibodies in autoimmune disease
(2010-11-11)
Patients with the systemic autoimmune diseases systemic lupus erythematosus (SLE) and Sjögren’s syndrome (SS) often have autoantibodies against Ro/SSA (composed of the TRIM21/Ro52 and Ro60 antigens) and La/SSB. The biological ...
Neuroblastoma incidence, biology and outcome : with special emphasis on quantitative analysis of tyrosine hydroxylase mRNA in blood and bone marrow
(2009-05-14)
Neuroblastoma, the most common malignant disease of early childhood,
accounts for 6% of childhood malignancies but is responsible for 9% of
paediatric cancer related deaths. The tumour originates from cells in the
neural ...
Tuberculosis in Stockholm : studies on transmission, prevention and control
(2013-05-08)
The first priority of tuberculosis control programs is diagnosis and treatment of all individuals with active tuberculosis. Contact tracing constitutes the second priority of tuberculosis prevention and control. Patients’ ...