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The mouse oocyte as a model in reproductive toxicology studies
(2007-10-18)
It is suspected that certain chemicals may cause alterations in female
reproduction, including ovarian failure and birth defects. Sub-fecundity,
infertility, pregnancy loss, fetal growth retardation, and birth defects
are ...
Synaptic transmission and synaptic plasticity in the mouse striatum
(2008-03-05)
The striatum is the major input nucleus of the basal ganglia and can be subdivided into a dorsal part and a ventral part that is also named nucleus accumbens (NAc). The dorsal part is involved in motor control and habit ...
Reproductive health in adolescent girls with special emphasis on menstrual disorders, bone health, sexuality and social factors
(2009-05-11)
Menstrual disturbances are common during adolescence, especially within the first 1-3 years after menarche, and are often explained by immaturity of the hypothalamic-pituitary-gonadal axis. However, little is known about ...
Structural bases for MHC class I peptide selection and neoepitope formation
(2018-04-13)
One task of the immune system is to distinguish between healthy cells and altered cells due to viruses or cancers. To achieve this CD8+ T-cells are constantly monitoring the Major histocompatibility class I (MHC-I) complexes ...
Elicitation and enhancement of T and B cell responses
(2012-10-05)
The Major histocompatibility complex class I (MHC-I) has been characterized in such great depth that a number of its key properties are well understood and part of its behavior can even be predicted. It is therefore ...