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Anaesthesia and analgesia for surgery in rabbits and rats : a comparison of the effects of different compounds
(2008-05-09)
Studies of anaesthesia and analgesia in rats and rabbit were undertaken
with the aim to improve anaesthesia techniques, for better animal welfare
and research quality.
Induction of anaesthesia with the volatile ...
Drug administration and blood sampling for pharmacokinetic studies in pediatric cancer patients
(2009-11-20)
This thesis focuses on drug administration and blood sampling for pharmacokinetic studies in pediatric cancer patients. Only about one third of the drugs used to treat children have been adequately tested with sufficient ...
Structural maintenance of chromsomes : a complex tale of genomic integrity
(2009-04-03)
Genomic integrity is an absolute requirement for cell survival.
Programmed events such as genome rearrangements and DNA replication can
cause lesions in the DNA, as can exogenous agents such as radiation and
chemicals. ...
Drug use in institutionalized and home-dwelling elderly persons
(2012-05-15)
The overall aim of this thesis is to investigate drug use in institutionalized and home- dwelling elderly, with a special focus on dementia. The major findings from the separate studies are summarized below.
Study ...
Human pluripotent stem cells : effects of handling and microenvironment
(2012-10-25)
Pluripotent stem cells hold great promise in regenerative medicine and drug development due to their developmental potential towards multiple lineages. However, there are still hurdles to overcome before these cells are ...