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Aspects of immune activation in HIV-1 infection
(2007-05-25)
Abnormal immune system activation is central in HIV-1 pathogenesis leading to CD4+ T-cell depletion and inappropriate immune responses. Disease stage and HIV load strongly correlate with the immune activation level which ...
Fetal echo doppler for early detection of congenital heart block
(2010-04-16)
Background: Fetal echo Doppler methods detecting prolonged atrioventricular (AV) time intervals, a mechanical PR interval corresponding to the electrical PR interval in ECG, have been proposed for surveillance of pregnancies ...
Studies on the mechanisms of carcinogenesis and cancer cell death
(2013-02-05)
Gastric cancer is the second most common cause of cancer-related mortality in the world. The mechanisms of gastric carcinogenesis are not fully elucidated. Telomerase and its catalytic subunit telomerase reverse transcriptase ...
Methodological aspects on carotid artery intervention
(2017-02-17)
In Sweden, approximately 25000 patients suffer a cerebral infarction (stroke) annually. Stroke ranks as the third-leading cause of death, and is the leading cause of functional impairment. Carotid artery stenosis accounts ...
Congenital heart block : a study of diagnostics, pathogenesis, prognosis and treatment
(2014-05-15)
Congenital heart block (CHB) is a rare condition with considerable mortality. In most patients the disease is associated with fetal exposure to maternal SSA-Ro and/or SSB-La autoantibodies (AB) and develops in fetal life. ...
SARS-CoV-2 viremia in patients hospitalised for COVID-19
(2023-01-12)
More than 6.6 million people have died from Covid-19 since the SARS-CoV-2 outbreak started in Wuhan, China, late 2019. The spread of the novel virus necessitated knowledge on how to manage this new disease. This project ...
European knowledge transfer reflected by research collaboration and patent citations indicators
(2011-02-28)
Knowledge transfer consists of activities that aim to capture and transmit knowledge, skills and competence from those who generate them to those who will transform them into socio-economic outcomes. In the context of the ...
Biological therapy in rheumatoid arthritis : epidemiological studies
(2014-05-09)
The landscape of RA treatment has unquestionably changed dramatically during the last decade. A deeper understanding of the pathophysiological and immunological mechanisms in RA, earlier and more aggressive treatment, and ...
Exploring the role of vitamin E in Alzheimer’s disease : an epidemiological and clinical perspective
(2012-05-10)
Vitamin E, the main non-enzymatic lipophylic antioxidant in the human body, has a major role in protecting the brain from damage mediated by free radicals. The term vitamin E encompasses eight natural congeners (forms): ...