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Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
Haematological malignancies constitute approximately 7% of all cancer cases in Sweden, and leukaemia is in fact the most common malignancy among children. The few established risk factors, such as ionising radiation and ...
Molecular studies of complications in end stage renal disease : focus on expression and variations of candidate susceptibility genes
(2005-09-09)
End stage renal disease (ESRD) is a complex multifactorial disorder, where both environmental and genetic factors are contributing to the phenotype. The most common complications seen in ESRD patients are malnutrition, ...
Development of novel PET radioligands for visualizing beta cell mass and amyloid plaques
(2016-08-19)
The aim of the thesis was twofold. The first aim was to radiolabel small molecules by using carbon-11 and fluorine-18 for visualising beta cell mass (BCM) in the pancreas by PET. Diabetes Mellitus (DM) is a chronic metabolic ...
Assessment of dopamine and serotonin release in the non-human primate brain using PET
(2011-01-12)
The molecular imaging technique positron emission tomography (PET) allows for non-invasive examination of biochemical markers in the living brain. For over three decades PET studies have provided important insight into the ...
PET studies on the mechanisms of action of antidepressant and antipsychotic drugs
(2017-10-06)
Positron emission tomography (PET) is a non-invasive molecular imaging technique suitable for examination of neurochemical biomarkers in the living brain. Among these applications, PET studies are used to facilitate the ...