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The diagnostic performance of prostate-specific antigen (PSA) in early detection of prostate cancer : considerations of sensitivity, specificity, lead-time and survival
(2003-09-19)
Background: Prostate cancer (PC) is the most common form of cancer, as well as the single major cause of cancer-related mortality among Swedish males. Recent reports indicate that screening of the serum levels of ...
Studies of effector functions in mycobacterium tuberculosis-infected macrophages with implications for host-directed therapies
(2019-02-15)
Tuberculosis infection remains a global health problem and the emergence of multidrugresistant TB (MDR-TB) adds further challenges in the battle to stop the spread of infection. Macrophages are the primary host cells to ...
Heart failure : studies of prognosis and advanced therapy
(2017-03-09)
Background: Heart failure (HF) is a major health problem affecting 2-3% of the Western population. The clinical syndrome of HF is associated with reduced (HFrEF) or preserved (HFpEF) ejection fraction. Around 50% of the ...
The role of human cytomegalovirus infection in cancer
(2013-05-20)
Cancer is a major cause of morbidity and mortality worldwide. It is thought that up to 20% of cancers are caused by infectious agents, and an oncogenic role of several viruses has been established for certain tumours. ...