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Characterization of a putative tumor suppressor region identified by the elimination test on human 3p21.3
(2003-05-02)
An experimental system, called the elimination test (Et), was developed to identify tumor growth antagonizing genes. Chromosome 3 containing microcell hybrids (MCHs) were passaged through SCID mice and regular deletion of ...
Quantitative methods for profiling dynamic chromatin features
(2022-05-12)
Living systems, from entire organisms down to the single cells constituting them are dynamic entities that continuously adapt and respond to their local environment. Cells achieve this through gene expression programs ...
Genetic predisposition to immune cell malfunction and inflammation
(2021-09-10)
Our genome contains all the instructions to control the synthesis of proteins, the development of cells and the interaction between body systems. We are armed with an immune system, made up of cells, chemical compounds and ...