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Quantitative methods for profiling dynamic chromatin features
(2022-05-12)
Living systems, from entire organisms down to the single cells constituting them are dynamic entities that continuously adapt and respond to their local environment. Cells achieve this through gene expression programs ...
Lessons from diagnosis-prescribing and antibiotic resistance surveillance in Ujjain, India : the lull before the storm
(2012-05-02)
Background: The evolution of antibiotic resistance is a global public health crisis building over decades. In this build-up antibiotic use has been the main driver for antibiotic resistance. To develop context-specific ...
Antibiotic prophylaxis in dentistry for the prevention of infective endocarditis
(2023-03-30)
In many parts of the world, it is praxis to administer prophylactic antibiotics prior to invasive dental procedures to reduce the risk of postoperative infective endocarditis (IE) among at-risk individuals. Such endocarditis ...
Behavioural outcomes of treatment with selective serotonin reuptake inhibitors
(2021-12-13)
Mood and anxiety disorders are some of the biggest contributors to morbidity worldwide, and may be lethal. Appropriate treatment is therefore paramount. Antidepressant medications constitute the primary pharmacological ...
Structural and functional studies of Malassezia sympodialis-derived allergens
(2008-03-21)
Atopic eczema (AE) is a chronic inflammatory skin disease characterised
by pruritic (itchy) skin lesions. The pathogenic mechanisms underlying AE
are still unclear, although several factors such as genetic
predisposition, ...
Abnormal coagulation and platelet function in patients with severe traumatic brain injury
(2016-03-22)
Traumatic brain injury (TBI) is associated with a high mortality and severe long-term morbidity in
survivors. TBI often affects previously healthy young persons, and represents one of the most
common causes of death among ...
Early indicators for adverse development of cardiovascular, renal and metabolic function in children born with low birth weight
(2018-08-17)
Prematurity affects more than 10% of infants worldwide and is the main reason for neonatal mortality. Improvements in neonatal care have led to higher survival rates into adulthood. Adverse events during organogenesis and ...
Antibiotic resistance and environmental factors : focusing on the situation in Odisha, India
(2012-05-24)
Background: The rise of antibiotic resistant bacteria is a major challenge to global public health. The environment has a significant impact on health and infectious diseases; however, there is a lacuna of information on ...
Obesity in childhood : psychosocial consequences and premature mortality
(2020-10-21)
Background: It is estimated that 91 million children worldwide will have obesity by 2025. Obesity in childhood is associated with increased risk of obesity in adulthood, psychosocial maladjustment, mental health problems, ...
Exploring the role of vitamin E in Alzheimer’s disease : an epidemiological and clinical perspective
(2012-05-10)
Vitamin E, the main non-enzymatic lipophylic antioxidant in the human body, has a major role in protecting the brain from damage mediated by free radicals. The term vitamin E encompasses eight natural congeners (forms): ...