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In silico analysis of pathways targeted by EBV infection and malignant transformation
(2009-10-23)
Epstein-Barr virus (EBV) is a ubiquitous γ-herpes virus with dual cell tropism for human B-lymphocytes and epithelial cells. EBV infection is linked to several malignancies such as Burkitt s lymphoma (BL) and nasopharyngeal ...
Studies on cholesterol and lipoprotein metabolism : emphasis on diabetes and sugar
(2015-05-08)
Cholesterol has important functions in the body; as a precursor in the synthesis of steroid hormones and bile acids (BAs), and as a component of cellular membranes. However, an elevated level of plasma cholesterol, transported ...
Effects of cigarettes, e-cigarettes and Swedish snus on vascular function
(2018-07-17)
Cigarette smoking is considered one of the leading causes of preventable morbidity and premature death worldwide. A large portion of this is attributable to cardiovascular disease such as ischemic heart disease and stroke. ...
Elucidation of the cell signaling pathways mediating innate immunity and host-pathogen interactions
(2019-03-14)
The ability to generate a robust immune response is integral to organismal homeostasis. Cells of the innate immune system are considered the first responders of immunity, and are therefore responsible for sensing both ...