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Evaluation of reverse transcriptase assay for viral load monitoring
(2007-05-17)
Retaining an active reverse transcriptase (RT) enzyme is a fundamental requirement for all retroviruses to replicate. Bearing in mind that HIV has a very high propensity to mutate measuring RT activity to determine the ...
Patient experiences and the influence on health literacy and self-care using mHealth to manage symptoms during radiotherapy for prostate cancer
(2019-02-01)
Introduction: Prostate cancer is a diagnosis that can affect the men’s quality of life both due to the symptoms related to the disease and the treatment the men receive. Treatment with radiotherapy for prostate cancer in ...
Viral wheeze and risk factors for childhood asthma : an evaluation of clinical, immunological and genetic factors
(2016-11-18)
It’s not fully understood why some children wheeze with viral infections, and why some develop severe asthma. In this study we compared two study groups; children presenting with acute wheeze (AW) before the age of four ...
Lumbar fusion for chronic low-back pain in isthmic spondylolisthesis
(2008-11-21)
Manifestation of isthmic spondylolisthesis (IS), with a prevalence of 5% in the general population, varies from totally asymptomatic to severe disability. Although fusion has positive short-term effects, the long-term ...
Acute kidney injury after coronary artery bypass grafting and outcomes
(2015-02-12)
Acute kidney injury (AKI) is a rapid reduction in glomerular filtration rate (GFR) that leads to a rise in serum creatinine (SCr). Acute kidney injury is common and patients with sepsis and patients who undergo cardiac ...
Prognostication in heart failure across ejection fraction phenotypes and challenging subgroups : data from the Swedish heart failure registry
(2022-05-10)
Background: The growing prevalence of heart failure (HF) worldwide determines an increasing burden on healthcare systems. HF phenotypes differ for several patient characteristics. Treatments with proven efficacy are mainly ...
Antibody responses to Plasmodium falciparum as markers of exposure and tools to monitor malaria transmission
(2018-09-28)
Plasmodium falciparum malaria has the highest death toll of all human parasitic diseases and nearly half of the global population is living at risk of infection. Reducing the malaria burden with the goal of achieving ...
Deciphering the transcriptional regulation code in colorectal cancer genome
(2014-03-06)
Colorectal cancer (CRC) is the third most common cancer type to threaten life for both men and women in the developed world. The molecular mechanism of CRC is very complicated and involves changes in different categories ...
Genetics and biomarkers of frailty : towards individualized management of the frailty syndrome
(2023-10-09)
Frailty is an age-related, dynamic state of multisystem physiological decline and is a
strong predictor of disability and mortality. To move towards an individualized management
of frailty, a better understanding of its ...
Copeptin in cardiovascular disease and dysglycemia
(2021-11-15)
Background: The impaired prognosis in patients with cardiovascular disease (CVD) and dysglycemia is not fully explained by traditional risk markers, among them hyperglycemia and hyperlipidemia. Understanding the developmental ...