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Detailed structural studies towards the understanding of lipopolysaccharide glycan expression in non-typeable Haemophilus influenzae
(2008-02-22)
Haemophilus influenzae (Hi) is a host-adapted Gram-negative bacterium that regularly colonizes the respiratory tract of humans. Hi is an important cause of disease worldwide and exists in encapsulated and unencapsulated ...
The role of the tumor suppressor gene, FBW7, and mechanisms of its inactivation in cancer
(2011-05-17)
The F-box protein FBW7 is a tumor suppressor and SCF ubiquitin ligase targeting several key oncoproteins for proteasomal degradation. In this thesis we addressed whether the FBW7 gene is inactivated by mutations in various ...
Swedish moist snuff and the risk of cardiovascular diseases
(2007-10-19)
The snuff consumption in Sweden has increased substantially during recent
decades and today more than every fifth male adult uses snuff daily.
However, the evidence on health effects from long-term use of snuff is
limited, ...
Low back pain among industrial workers : occupational health studies on prevalence, incidence, and associations with work and lifestyle in I.R. Iran
(2007-02-23)
This thesis presents the results from a prospective industrial population
cohort study on epidemiology and risk factors for low back pain (LBP) in
Iran. The four papers in the thesis were based on a cross-sectional
survey ...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular ...
Aspects on chronic stress and glucose metabolism in women with recurrent vulvovaginal candidiasis and in women with localized provoked vulvodynia
(2007-04-06)
Objective: To evaluate the degree of stress in women with recurrent vulvovaginal candidiasis (RVVC) and in women with localized provoked vulvodynia (LPV) (former vulvar vestibulitis syndrome) compared with controls. To ...
Oral mucositis and periodontal disease in patients with primary or acquired immunodeficiencies
(2013-09-11)
The infection and inflammation in the oral cavity are commonly related to the skewed interaction between host immunity and inhabiting microorganisms. Both primary and acquired immunodeficiency conditions are frequently ...
Morbidity in Ménières disease : aspects on quality of life and triggering factors
(2002-11-22)
Menieres disease is an inner ear disorder of unclear origin, characterized by severe attacks of simultaneously appearing fluctuant hearing loss, vertigo, tinnitus and a feeling of aural fullness. The disease has a well-known ...
The glucocorticoid receptor as a regulator of cortisol responses in cortisol resistant patients and healthy subjects
(2013-03-18)
Glucocorticoids are essential for life, and are involved in growth, reproduction, intermediary metabolism, immune and inflammatory reactions as well as central nervous system and cardiovascular functions. Glucocorticoids ...
Intrinsic brain activity in health and disease
(2015-08-20)
The main part of the brain’s energy need is to support housekeeping functions and internal
information processing, regardless of external tasks. Cognitive brain imaging, aimed at relating
mental phenomena to neurophysiological ...