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Factors associated with brain tumor risk : with focus on female sex hormones and allergic conditions
(2008-09-03)
Every year approximately 1200 people in Sweden are diagnosed with a brain
tumor. The two main histological types of brain tumors, gliomas and
meningiomas, differ in terms of their localization, histology, prognosis,
and ...
Mitochondrial dysfunction in ageing and degenerative disease
(2007-10-05)
The cytoplasm of eukaryotic cells contains a dynamic network of
double-membraned organelles, called mitochondria, which perform the
process of oxidative phosphorylation (OXPHOS) that provides cellular
energy in the form ...
Generation and transmission of mtDNA mutations and their effect on aging
(2013-12-20)
Mutations in mtDNA are known to cause neuromuscular diseases and have been associated with several common age-associated diseases as well as being a contributor to the aging process. Despite their importance there are still ...
Mitochondrial DNA mutations : brain developmental and ageing consequences, and possible treatments
(2012-09-06)
Ageing is a complex process that involves cellular senescence, a gradual loss of tissue homeostasis, and decline in organ function. Abundant evidence implicates mitochondria in ageing suggesting: (i) accumulation of ...