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Therapeutic applications of acoustic and electromagnetic energy
(2005-02-10)
This thesis focuses on techniques based on electromagnetic and acoustic energy for treatment of a variety of diseases, including development of new techniques as well as improvement and evaluation of existing techniques. ...
Mitochondrial dysfunction in ageing and degenerative disease
(2007-10-05)
The cytoplasm of eukaryotic cells contains a dynamic network of
double-membraned organelles, called mitochondria, which perform the
process of oxidative phosphorylation (OXPHOS) that provides cellular
energy in the form ...
Neonatal respiratory control : inspiration, inflammation and the prostaglandin E2 pathway
(2014-10-22)
Immature or deficient autonomic control is a common problem in infants born at a premature age, and is of central importance in apneas. The pre- and perinatal development of the brainstem neural circuits that control ...
Molecular insights into mitochondrial DNA replication
(2012-05-07)
Mitochondria are organelles found in eukaryotic cells. These organelles produce most of the adenosine triphosphate that cells use as a source of energy. Mitochondria contain their own genomic material, a circular DNA genome ...
The interface of mitochondrial DNA transcription and replication
(2012-11-20)
Mitochondria are a dynamic network of subcellular organelles that produce the
majority of cellular ATP through the process of oxidative phosphorylation (OXPHOS).
The components of the respiratory chain are encoded by two ...
Congenital adrenal hyperplasia : pre-and postnatal treatment effects on cognition, behavior and brain resting-state functional connectivity
(2022-04-14)
Congenital adrenal hyperplasia (CAH), an autosomal recessive disorder affecting adrenal steroid synthesis, is linked to impaired adrenal synthesis of cortisol and aldosterone. The increased production of androgen precursors ...
Long-term effects of pre- and postnatal glucocorticoid treatment in congenital adrenal hyperplasia
(2019-02-15)
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder mostly caused by mutations in the CYP21A2 gene leading to impaired production of cortisol and aldosterone. Precursors in the steroidogenic pathway are ...
Mitochondrial dysfunction and treatment strategies
(2016-11-18)
The mitochondria are essential for cellular energy production and are involved in many processes in the cells. The mitochondria contain their own DNA (mtDNA) that is vital for oxidative phosphorylation since it encodes ...