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The moral enterprise in intensive care nursing
(2004-05-19)
The aims of this thesis were to explore nurses' experiences of stress in the ICU (I), to analyze experiences of moral concerns in intensive care nursing from the perspective of relational ethics (II), to describe the ...
Exposure assessment : gender and context, and target groups for prevention of neck/shoulder and low back pain
(2006-01-26)
Neck/shoulder and low back pain are the most frequent sources of pain complaints, health care utilization, and lost work time. The etiology is multifactorial, and includes physical and psychosocial working conditions, ...
Klebsiella pneumoniae and Escherichia coli : multidrug-resistance and different aspects of invasive infections
(2016-05-02)
Klebsiella pneumoniae and Escherichia coli are pathogens belonging to the Enterobacteriaceae family. They can cause infections ranging from uncomplicated urinary tract infection to severe bloodstream infection (BSI). The ...
Studies on apolipoprotein E and high cholesterol diet as risk factors for neurodegeneration
(2005-12-30)
Elevated level of plasma cholesterol is a well-established risk factor for cardiovascular disease, and emerging evidence suggest that it plays a role in the pathogenesis of neurodegenerative diseases, including Alzheimer's ...
Measurements of physical workload with special reference to energy expenditure and work postures
(2011-01-27)
Background: There is a need in preventive ergonomics for accurate and valid methods of quantifying exposure to physical workload.
Aims: Two technical instruments were evaluated for quantifying occupational physical ...
Alzheimer disease : subcellular Aβ mechanisms and treatment strategies
(2023-02-01)
The amyloid β-peptide (Aβ) is the key molecule in the pathogenesis of Alzheimer disease (AD), but the mechanisms of its toxicity are still largely unknown. This thesis includes studies aimed at studying Aβ induced mechanisms ...
Immunoregulatory effects of placenta-derived decidual stromal cells
(2016-01-08)
Decidual stromal cells (DSCs) play a pivotal role in feto-maternal tolerance to prevent rejection of the fetus during pregnancy. This provides a rationale for immunomodulatory stromal cells from the placenta being isolated ...
From quality control to neurodegeneration : regulation of autophagy and the DNA damage response by ubiquitin-modifying enzymes
(2020-05-18)
Protein homeostasis and genome integrity are safeguarded by a variety of cellular quality control pathways. While protein quality is controlled by a delicate balance between protein biosynthesis, folding and degradation, ...