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Immunological studies on anca-associated vasculitis with special reference to T cell activation
(2009-10-16)
This thesis focuses on the role of T cells in ANCA-associated vasculitis. We initially investigated activation markers on T cells in patients with Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and renal ...
Formal and informal care in an urban and a rural elderly population : who? when? what?
(2007-08-31)
This thesis explored informal and formal care in relation to physical and
mental functioning in an urban and a rural setting in Sweden. Three
different study populations were used: eight cohabiting couples where one
of ...
DNA repair by HDR in experimental tumorigenesis
(2008-05-15)
The aim of this thesis was to further understand how defects in the homology-directed repair (HDR) pathway affect tumor formation and development. To study proteins involved in HDR is challenging since most of its members ...
Go with the flow : to facilitate learning in laparoscopic gynecology
(2013-05-22)
Background: Education in medicine, particularly in surgical disciplines, is crucial since it affects patient safety. The learning process is dependent on individual abilities, prior knowledge and the learning environment. ...
Modulation of invariant NKT cell activity by cytokines and receptors in human disease
(2010-08-27)
Invariant natural killer T (NKT) cells are innate-like lymphocytes with both immunoregulatory and cytotoxic functions that play a role as activators and regulators of the immune response in many diseases. NKT cells are ...
Studies on neuroimmune interactions in allergic inflammation with focus on neurotrophins
(2006-09-29)
Allergic asthma is a chronic airway disease characterized by an eosinophilic inflammation, bronchoconstriction, increased mucus production and bronchial hyperreactivity. The disease involves several mediators and cell types ...
Web-based studies of lifestyle factors and immune function
(2011-01-17)
Upper respiratory tract infection (URTI), is estimated to cost $40 billion per year in the US, not including the cost of influenza, and is the most common reason for seeking primary care in many countries. Despite this, ...
Cultural explanatory model of depression among Iranian women in three ethnic groups (Fars, Kurds and Turks)
(2010-05-20)
Background: As one of the most prevalent diseases globally and as an important cause of disability, depressive disorders are responsible for as many as one in every five visits to primary care. However, the true figures ...
Muscular aging and its relation to physical activity and function : longitudinal and cross-sectional analyses
(2021-11-09)
With age, muscle mass decreases and muscle function and strength decline, which is associated with loss of independence, hospitalization, morbidity and mortality. The aim of this thesis was to investigate the mechanisms ...
Intracellular pathways involved in formation and degradation of prions
(2009-10-23)
Prions cause invariably fatal neurodegenerative diseases, in which a misfolded host-encoded protein appears to be the main, if not the only, component of the infectious agent. During disease, a normal cellular protein, ...