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The many faces of p57Kip2 : acting in apoptosis, differentiation and cytoskeleton reorganisation
(2009-08-28)
p57Kip2 is a known cyclin dependent kinase inhibitor, which has been suggested to be a tumor suppressor gene. Indeed various human cancers show a reduction in p57Kip2 expression, indicating that this protein might be of ...
Performance and trainability in paraplegics : motor function, shoulder muscle strength and sitting balance before and after kayak ergometer training
(2006-11-17)
Background: Spinal cord injury (SCI) results in a complete or partial loss of motor and/or sensory function below the injury level. An SCI causes extensive functional impairment compelling many persons to wheelchair usage. ...
Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
(2009-01-09)
Rheumatoid arthritis (RA) is a complex disease with autoimmune features primarily causing destruction in the joints of the body. Knowledge regarding risk indicators and causes are increasing but so far only a few genetic ...
Hereditary predisposition and prognostic prediction in cancer
(2021-11-23)
Cancer is a genetic disease. The cancer cells evolve clonally through changes of their genome, gaining malignant characteristics. In hereditary cancer syndromes, a genetic aberration which puts the cells one step closer ...
Genetic association and linkage studies in colorectal cancer
(2014-10-23)
Colorectal cancer (CRC) is the third most common cancer type in the Western world. Over one
million patients are diagnosed worldwide yearly. A family history of CRC is a major risk factor for
CRC. The total genetic ...