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Performance and trainability in paraplegics : motor function, shoulder muscle strength and sitting balance before and after kayak ergometer training
(2006-11-17)
Background: Spinal cord injury (SCI) results in a complete or partial loss of motor and/or sensory function below the injury level. An SCI causes extensive functional impairment compelling many persons to wheelchair usage. ...
Clinical studies in multiple myeloma
(2016-09-23)
Multiple Myeloma (MM) is an incurably disease of the bone marrow. It is characterized by the uncontrolled growth of clonal plasma cells (PCs) and leads to production of non-functional gammaglobulin. Clinical features include ...
Role of posttranslational modifications in regulation of Notch and transcriptional coactivator mastermind-like 1
(2011-12-29)
The Notch signaling is an evolutionary conserved pathway enabling short range cell-cell interactions, crucial for diverse developmental and physiological processes during embryonic and adult life. The Mastermind-like (MAML) ...
Transcriptional and epigenetic regulation of gene expression by arsenic in cancer and normal cells
(2016-02-18)
Inorganic arsenic is a toxic metalloid that occurs naturally on the earth’s crust. Millions of people worldwide are exposed to inorganic arsenic via drinking water, and more recently also via contaminated food, in particular ...
Acute encephalitis in childhood : clinical characteristics and outcome with special reference to tick-borne encephalitis
(2014-05-05)
Acute encephalitis is relatively uncommon but potentially devastating. The prognosis varies from complete recovery to severe sequelae or death. The diagnosis is difficult to establish and the etiology often remains unclear. ...
Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease
(2006-11-10)
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased ...
Health outcomes of women with breast cancer
(2014-12-17)
The overall survival of breast cancer patients has increased quite remarkably in the past decades in the developed countries due to substantial improvements in diagnosis and treatment. As a consequence, the proportion of ...
Linker histone H1 and androgen receptor : two different players in the chromatin orchestra
(2012-05-23)
The linker histone H1 and the androgen receptor are two different players in the chromatin orchestra. The linker histone H1, one of the most abundant proteins in the nucleus, is located at the surface of the nucleosome but ...
Biomarkers for CNS metastasis in non-small cell lung cancer (NSCLC)
(2020-11-18)
Non-small cell lung cancer (NSCLC) comprises more than 75% of lung cancer cases and is usually diagnosed in advanced stages. Lung cancer is the leading cause of cancer death among all solid tumours and the second most ...
Interference control in working memory : neurobehavioral properties and age differences
(2018-11-08)
This doctoral thesis aimed to investigate the basic processes of interference control (IC) in working memory (WM). We sought to unravel some of the underlying mechanisms of IC by examining brain correlates, while also ...