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Cholangiocarcinoma in primary sclerosing cholangitis
(2001-10-05)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. ...
Pharyngeal surgery and epidemiology in sleep apnea
(2012-08-13)
Obstructive sleep apnea syndrome (OSAS) occurs frequently among adults and children. The first-line treatments in adults are continuous positive airway pressure (CPAP) or mandibular retaining devices (MRDs), but the long-term ...
Risk factors for rheumatoid arthritis : epidemiological studies of perinatal characteristics, infections and the inflammatory reflex
(2009-11-13)
Rheumatoid arthritis (RA) is a chronic inflammatory disease that is characterised by symmetric polyarthritis leading to progressive joint destruction. The aim of this thesis was to contribute to better knowledge of the ...
A study of biomarker analysis in association with type 1 diabetes and their shared features in rheumatoid arthritis
(2014-10-03)
Type 1 diabetes (T1D) is mediated by abnormal immune system (autoimmunity) that targeting specifically to self insulin-producing cells (β-cells). People with T1D require treatments based on life-long insulin substitution. ...
Socioeconomic determinants of health : a matter of economic or social capital?
(2011-11-16)
Background: There is currently a growing interest in the role of social structures, social conditions and social relationships in explaining patterns of population health, as well as the need to connect individual health ...
Methods development for the investigation of the mammalian genome radial architecture : the quantitative side
(2021-04-16)
The nucleus of mammalian cells cradles the genome, an ensemble of nucleic acid macromolecular polymers that store information in a physical form. For a cell to perform life-sustaining processes, reading and utilizing the ...