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Host-pathogen interactions in severe group A streptococcal infections
(2007-12-28)
Streptococcus pyogenes, also called group A Streptococcus (GAS), is an important human pathogen ranked number 9 on the list of global killer pathogens. It causes a wide spectrum of disease, including uncomplicated superficial ...
Acyl-CoA thioesterases : auxiliary enzymes in peroxisomal lipid metabolism
(2007-05-18)
Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly related to lipid metabolism, including α- and β-oxidation as well as the first steps of plasmalogen biosynthesis. Peroxisomal ...
Functional characterization of a peroxisomal acyltransferase gene family
(2008-10-24)
Peroxisomes are cell organelles that play an important role in the metabolism of a variety of lipids including very long chain fatty acids, dicarboxylic acids, bile acids, and xenobiotic carboxylic acids. The metabolism ...
The mammalian peroxisome : ‛its function and distribution’
(2010-12-07)
Peroxisomes are essential organelles for normal cell functions in all organisms from yeast to human. Their important contribution in different metabolic pathways is clearly visible by the severe phenotypes seen in the ...
Clinical use of prognostic markers in head and neck cancer
(2022-05-12)
Head and neck cancer (HNC) is a heterogeneous group of tumors where squamous cell carcinoma is the most dominant. In 2020, 1640 new cases of HNC were reported in Sweden which accounted for 2.3% of the total cancer incidence. ...
Peroxisomal and mitochondrial enzymes involved in lipid metabolism : studies on function and regulation
(2013-11-05)
Fatty acids constitute a major part of the energy that we obtain from the diet and are also the principal source for mammals to store energy. To use the incoming or stored fatty acids as energy, the fatty acids needs to ...
Immunological responses in genital HPV infections and etiology of cervical cancer
(2005-05-13)
Cervical cancer is one of the most common forms of cancers in women. Every year approximately 450,000 women are diagnosed worldwide and 200,000 die. The sexually transmitted oncogenic human papillomavirus (HPV) types are ...
Studies on the presence and influence of human papillomavirus (HPV) in head and neck tumors
(2005-03-18)
The aim of this thesis was to confirm the presence of human papillomavirus (HPV) in tonsillar cancer and the previous finding that presence of HPV in tonsillar cancer is prognostic favorable for patient survival. Furthermore, ...
Concepts in DNA immunization overcoming viral diversity and enhancing plasmid immunogenicity
(2004-05-07)
On April 23, 1984, the prominent scientist Robert Gallo held a historical press conference at the Department of Health and Human Services, Washington D.C., USA. He announced that his laboratory at the National Institutes ...
Studies on human papillomavirus and molecular markers in head-neck cancer
(2015-03-03)
Background: Oropharyngeal squamous cell carcinoma (OSCC), where tonsillar and base of tongue cancer (TSCC and BOTSCC) dominate, is associated with smoking and alcohol as well as human papillomavirus (HPV) infection. The ...