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Dermal exposure determinants : a pesticide exposure assessment approach for developing countries
(2008-11-26)
Background: We know little about the levels of exposure to pesticide in
subsistence farmers mainly because of lack of easy to use and low cost
pesticide exposure assessment methods.
Aim: This thesis aimed to develop ...
Familial risks for cancer with reference to lung cancer
(2004-10-15)
Familial aggregation of cancer may be due either to environmental factors shared by family members, or to shared genes. Familial clustering has been an avenue to the understanding of the etiology of cancer and has been a ...
Post-translational modification of estrogen receptor alpha and p53 in breast cancer cells
(2015-08-21)
Estrogen receptor α (ERα/ESR1) and tumor protein p53 (p53/TP53) signaling are aberrant and play important roles in breast cancer pathogenesis and evolution. ERα is highly expressed in the majority of breast cancers and is ...
Extrahepatic cytochrome P450s : relation to cancer susceptibility
(2003-09-19)
Cytochrome P450 (CYP) enzymes in extrahepatic tissues may play important roles in regulating the capacity of individual cells to metabolize environmental carcinogens and hormones. In this thesis, we characterized the ...