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The human antimicrobial protein hCAP18/LL37 in wound healing and cell proliferation
(2005-08-26)
Epithelia constitute the principal barriers separating the host and the potentially injurious environment, and defence of this interface is therefore essential. Antimicrobial peptides are key effector molecules of the ...
The human gastric microbiota in health and disease
(2010-04-16)
The human body comprises of complex microbial ecosystems that have co-evolved with its host and play important roles in the maintenance of health and in the etiology and outcome of various disease states. The microbiota ...
Antimicrobial peptides and proteins in innate immunity : emphasis on isolation, characterization and gene regulation
(2005-03-18)
Antimicrobial peptides are endogenous antibiotics and effector molecules
of Innate immunity. These peptides are mainly localised to epithelial
linings and circulating neutrophils. They kill microbes by disruption of
their ...
Leukocyte activation in newborns in relation to prenatal stress
(2009-11-05)
The aim of this project is to describe the pattern of innate immunity responses at birth with focus on the recruitment of leukocytes such as eosinophils and neutrophils and their content of cathelicidin antimicrobial peptide ...
Studies of the role of the cathelicidin peptide LL-37 in epithelial biology
(2010-05-14)
The biology of epithelial immunity as well as of tissue repair is complex and highly regulated. A variety of molecules, cell types, and biological processes such as, cell differentiation, proliferation and migration, ...
Expression and regulation of antimicrobial peptides in mucosal immunity
(2012-10-25)
Antimicrobial polypeptides (AMPs) are effector molecules of the innate immune defense. AMPs are mainly expressed in epithelial cells and immune cells, providing the first line of defense to infection as direct antimicrobials. ...
Novel in vitro methods aiming at improving fertility preservation
(2021-11-11)
The well-established fertility preservative methods for female cancer patients include the cryopreservation of embryos, mature oocytes and ovarian tissue before the initiation of gonadotoxic cancer treatment. Due to a ...
WRAP53β and scaRNA2 on their journey to repair the DNA
(2018-03-22)
WRAP53β is a multifunctional protein involved in several cellular processes like Cajal body formation, telomere maintenance and DNA repair. WRAP53β is responsible for targeting factors to specific cellular locations, and ...
Genetic and cognitive aspects on recovery after propofol anaesthesia
(2015-01-14)
Propofol is one of the most used intravenous anaesthetics in the western world. It is often
used for ambulatory surgery due to favourable pharmacokinetic properties allowing quick
onset and short emergence time. However, ...
Cytokines in the nervous system with emphasis on interleukin-1 receptor-mediated activity
(2005-03-11)
Interleukin-1 (IL-1) is one of the most important pro-inflammatory cytokines and plays a pivotal role in the neuroinflammation associated with certain forms of neurodegeneration, such as epilepsy, cerebral ischemia, trauma, ...