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Pulmonary tuberculosis and Pneumocystis jiroveci pneumonia in HIV-infected patients in Ethiopia
(2007-02-12)
The objective of this study initially was to determine the prevalence of
culture-verified pulmonary tuberculosis in TB suspects and investigate
the impact of human immunodeficiency virus (HIV) infection on the
prevalence, ...
Side-chain oxidized oxysterols as metabolic regulators in liver and brain
(2014-02-03)
Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half-life and their ability to pass lipophilic membranes easily, thus they are considered as important intermediates in cholesterol excretion ...
Identification and characterization of novel glomerulus-associated genes and proteins
(2010-09-17)
The kidney is responsible for sieving the circulating blood to eliminate water-soluble waste products and potentially toxic substances from the body. The filtration step occurs in specialized filtration units called ...
Studies on human sterol 27-hydroxylase with emphasis on its mechanism of regulation and metabolic consequences of a deficient enzyme
(2007-05-11)
Sterol 27-hydroxylase (CYP27A1) is a mitochondrial cytochrome P-450
enzyme present in most animal cells. In hepatocytes, CYP27A1 has an
important role in connection with biosynthesis of bile acids from
cholesterol. In ...
Proinflammatory and antigen-specific CD4+ T cells in rheumatoid arthritis
(2014-02-10)
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease primarily affecting peripheral joints. In this thesis work we aimed to increase the knowledge about proinflammatory and antigen-specific CD4+ T cell ...
Side-chain oxidized oxysterols as metabolic regulators in vivo
(2017-02-28)
Oxysterols are oxygenated derivatives of cholesterol characterized by a very short half- life and their ability to pass lipophilic membranes easily, and they are considered as important intermediates in the excretion ...
Determinants of hearing impairment in Swedish hunters : an e-epidemiological approach
(2016-04-08)
Background: 290 236 persons bought a hunting license in Sweden 2014/15. Hunters are
spread all over the country and come from all socioeconomic groups. Recreational fiearms
can produce peak noise levels between 156-164 ...
Regulation of molecular processes in diffuse large B-cell lymphoma
(2013-04-25)
The molecular understanding of diseases has advanced rapidly due to the use of gene expression profiling. However, these methods have been hampered by the limitation to use frozen tissue specimens. Formalin fixation and ...
Studies on the role of SOCS3 and STAT3 in development and function of the immune system
(2017-11-27)
The immune system is composed of an innate and an adaptive response that protects us from the microbial attacks. The innate system provides a fast defense against infection. However, many microbes evade or overwhelm the ...
Identification and characterization of kidney glomerulus-associated genes and proteins
(2012-07-06)
The kidney glomerulus is a micro-organ comprised of a molecular filtration barrier that prevents the loss of blood proteins into the primary filtrate. This function is dependent on the coordination of its three constituent ...