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Computed tomography based assessment of treatment response in solid tumors
(2012-08-28)
criteria (WHO-criteria) were launched in 1979 followed by the Response Evaluation Criteria In Solid Tumors (RECIST) in 2000 and the updated version RECIST 1.1 in 2009. There are, however, still several steps that may deteriorate consistencies...
CYP2C19 and CYP2C9 geno- and phenotypes in healthy Swedish and Korean subjects
(2010-12-23)
% of Korean alleles. The frequency of the CYP2C19*17 allele was very low in Koreans (0.3%) compared to Swedes (20%) and this allele caused an increased enzyme activity in the Swedish subjects. Among subjects homozygous for CYP2C19*1, Koreans displayed...
Pharyngeal surgery and epidemiology in sleep apnea
(2012-08-13)
% (ODI4) with home based sleep apnea registrations and daytime sleepiness with validated questionnaires (Epworth sleepiness scale, ESS), as well as complication and satisfaction rate, before and 1 year after UPPP in 158 patients. There was a significant...
MHC-class I restricted peptide-based immunomodulation of CD8+ T and NK cells
(2012-09-06)
The main aims of the immune system are to protect the host from potential threats by distinguishing self from non-self and altered-self. T cells and NK cells play a key role in the identification and elimination of threats ...
Cardiac rehabilitation in women
(2012-01-11)
The overall aim of this thesis has been to investigate the prognostic value of exercise capacity and whether a multifactorial rehabilitation program could affect traditional cardiac risk factors as well as self-rated health, ...
Clinical and pathophysiological aspects of intrahepatic cholestasis of pregnancy
(2012-11-20)
an observational study and compared the levels of active vitamin D (1,25-dihydroxy vitamin D3) in women with ICP and normal pregnancies. In Paper II we examined in a prospective case-control study morphological differences of placentas from untreated...
Anal incontinence and obstetric sphincter tears
(2010-10-15)
PURPOSE: To evaluate the prevalence of anal incontinence (AI) in primiparous women five years after their first delivery; to investigate if an 8-12 hour time delay of primary repair affects AI at 1-year follow-up; to study the association between...
Immunoreactive proteins in Taenia solium
(2012-02-02)
cysticercus was constructed in which 1,650 unique sequences were identified, 845 of them previously unknown. Also, 2-DE was performed and succeeded in detecting several immunogenic proteins, among which TsolHSP36 and Tsol-p27 were identified by liquid...
Epidemiological studies in Malaysia and Sweden on associations between smoking, silica exposure and the risk of developing rheumatoid arthritis
(2012-11-12)
between smoking and the HLA-DRB1 shared epitope (SE) alleles in the risk of developing ACPA+ RA. We also found that the most common SE allele in the Asian population, HLA-DRB1*0405, also showed signs of interaction with smoking with regard to risk of ACPA...
Visually induced ocular torsion
(2011-05-20)
There has been some controversy whether ocular torsion (eye rotation around the line of sight) is induced in response to a tilted visual scene. The aim of this thesis was to investigate if ocular torsion can be induced by ...