Search
Now showing items 1-10 of 126
Drug-resistance in M. tuberculosis and the characterisation of a new anti-tuberculosis drug-candidate
(2009-05-19)
The occurrence of multidrug-resistant (MDR) tuberculosis (TB) has been
increasing at alarming levels globally, and the spread of extensively
drug-resistant (XDR) M. tuberculosis is threatening the control of
tuberculosis. ...
Early cervical lesions detected by visual inspection : viral factors, management and follow-up
(2009-10-09)
Hospital, Kampala, Uganda. 824 screened positive and were referred for colposcopy, half were allocated to the intervention group and half to the control group. In the intervention group, information about the screening findings and a request to assist...
Young adults in urban Pakistan : barriers and challenges for improving health behaviors in the wake of the HIV/AIDS epidemic
(2010-08-26)
Background: HIV/AIDS is spreading globally more specifically among the
younger generation. The impact of HIV/AIDS on the youth cannot be
underestimated. According to the UNAIDS report 2008; an estimated number
of 33 ...
Effects of Alzheimer's and Parkinson's disease gene mutation on cell signaling
(2009-01-09)
Alzheimer's disease (AD) and Parkinson's disease (PD) are the major
neurodegenerative disorders affecting the elderly. The discovery of genes
causing familial forms of these disorders has contributed enormously
towards ...
New apheresis techniques in transplantation
(2008-11-21)
The shortage of organs for transplantation is a global problem and therefore it is of outmost importance to increase the number of donations and improve long term graft survival. As an effort to increase kidney donations, ...
Genome-wide study of HDACs and transcription in Schizosaccharomyces pombe
(2010-05-27)
The eukaryotic genome has to be organized to fit into the cell and this is achieved by packing of DNA into chromatin. The basic repeating structural unit of chromatin is the nucleosome, which consists of DNA wrapped around ...
Studies of the device perfect capsule in an animal model to reduce lens epithelial cell proliferation
(2008-09-12)
The sealed-capsule irrigation device, the Perfect Capsule, is a surgical
device designed to target lens epithelial cells (LECs) during cataract
surgery and prevent posterior capsule opacification (PCO). This is
especially ...
Fear commands attention : snakes as the archetypal fear stimulus?
(2010-04-01)
Information regarding successful solutions to environmental hazards has
accumulated in the gene pools of species, as a result of evolution.
Therefore, from an evolutionary viewpoint, fear has played a central role
in ...
Studies of histone modification systems in Schizosaccharomyces pombe
(2010-05-26)
150D the reverse transcripts decreased to 25% of wild type levels. In the double mutant dcr1delta/rpb7-G150D the reverse transcript levels remained low indicating that Rpb7 functions upstream of Dcr1 in the RNAi pathway that maintains the H3K9me2...
Genetic content of clinical pneumococcal isolates and its relation to disease outcome
(2009-09-30)
Streptococcus pneumoniae is a Gram-positive bacterium that can cause a wide range of diseases. These include otitis media, sinusitis, pneumonia and meningitis. It can, however, also cause asymptomatic carriage thereby ...