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Wnt signaling affects cell adhesion and neuronal differentiation
(2008-05-23)
-cell interactions of committed ectodermal cells. We also showed that expression of the Wnt PCP signalling gene Vangl2 (Van gogh-like 2) was increased. Wnt7a´s influence on neuronal differentiation was studied by investigation of β-tubulin III expression, a marker...
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
Dengue fever (DF) is the most common global viral mosquito-borne infection, with 100 million estimated cases annually in tropical and subtropical areas. The dengue viruses (genus Flavivirus, Flaviviridae) occur in 4 serotypes ...
Studies on ribonucleotide reductase, a target for anticancer therapy, with focus on electron donor aspects : thioredoxin and glutaredoxin systems
(2009-03-27)
Faithful replication of DNA and its repair are fundamental processes in
all living cells which utilize deoxyribonucleotides as DNA building
blocks. Ribonucleotide reductase (RNR) is the essential enzyme for de
novo ...
Aspects on latency in HIV-1 infection
(2010-04-16)
The use of combination antiretroviral therapy (ART) has resulted in a substantial reduction in viremia, a rebound of CD4+ T-cells and increased survival for human immunodeficiency virus type 1 (HIV-1) infected individuals. ...
Epidemiology and care of epilepsy in Vietnam
(2010-05-12)
Epilepsy is often considered the most common serious chronic neurological disorder estimated to affect 50 million people globally. Although the majority of these live in developing countries, data on the epidemiology of ...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
Brain mechanisms in pain regulation
(2009-10-02)
The subjective sensitivity to pain differs greatly between individuals and neuroimaging has contributed to the understanding of the cerebral mechanisms involved in pain regulation. The descending pain inhibitory circuitry ...
Molecular characterization of Mycobacterium tuberculosis complex isolates from Sweden
(2010-04-21)
Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex
(MTC), is a serious infection in man and animals. According to the World
Health Organisation (WHO), about one third of the world´s population is
infected ...
Traffic noise and cardiovascular disease
(2010-04-30)
Traffic noise is an increasing problem in urban areas worldwide, but health effects in relation to traffic noise exposure are not well understood. Several studies show that noise may give rise to acute stress reactions, ...
Dermal exposure determinants : a pesticide exposure assessment approach for developing countries
(2008-11-26)
Background: We know little about the levels of exposure to pesticide in
subsistence farmers mainly because of lack of easy to use and low cost
pesticide exposure assessment methods.
Aim: This thesis aimed to develop ...