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Manipulating neural stem cells
(2010-03-17)
miniaturized platform for culturing embryonic stem cells and adult neural stem cells. This platform contains 672 wells, each one holding 500nL. The volume, large enough to culture stem cells over several days is also small enough to drastically reduce reagent...
A longitudinal study of dentofacial morphology in young children treated for the obstructive sleep apnoea syndrome
(2008-09-19)
The most common cause of OSAS in children is enlarged tonsils and/or adenoids. Consequently, the treatment for OSAS in children with enlarged tonsils and/or adenoids is adeno-/tonsillectomy. The prevalence of OSAS in ...
Genome-wide study of HDACs and transcription in Schizosaccharomyces pombe
(2010-05-27)
The eukaryotic genome has to be organized to fit into the cell and this is achieved by packing of DNA into chromatin. The basic repeating structural unit of chromatin is the nucleosome, which consists of DNA wrapped around ...
Prognostic molecular markers of childhood leukemia
(2010-05-21)
and Oncology (NOPHO), we investigated the frequency and clinical implications of the genetic aberration dic(9;20)(p13.2;q11.2), which easily escapes detection by chromosome banding analysis alone. We obtained material and performed interphase FISH on more than...
Epidemiological and recovery facilitating studies of an urban population of stroke patients in Iran
(2010-05-28)
Introduction: Approximately 15 million people have a stroke annually in the world, of whom one third will die within one year and one third will suffer permanent disability. Over 85% of these deaths happen in people living ...
Erythropoietic protoporphyria clinical and epidemiological aspects
(2010-02-26)
Erythropoietic protoporphyria, EPP, is an inherited disease in which the main clinical manifestations are painful cutaneous sensitivity to intense light and liver disease which in some requires liver transplantation for ...
Studies on arterial endothelial function and intima-media thickness using ultrasound technique
(2008-05-09)
Background: The development of ultrasonographic arterial imaging, high-resolution B-mode ultrasonography, has created a technical basis for a new diagnostic approach to atherosclerotic disease by offering the possibility ...
Mechanism of pathological angiogenesis in adipose tissue and tumor
(2009-09-18)
Angiogenesis is critical for both malignant diseases, such as cancer, and non-malignant diseases, such as obesity and metabolic disorders. Majority of tissues and organs are highly vascularized. The malfunctions of tissue ...
The role of glucocorticoid receptors and mitogen-regulated protein kinases in the cochlea
(2009-08-21)
Hearing loss induced by acoustic trauma is a common handicap for the human population. Acoustic trauma triggers a cascade of changes in the cochlea such as a direct mechanical damage of sensory hair cells, biochemical ...
Studies on cysteinyl leukotriene receptor 1 and 15-lipoxygenase-1 in lymphomas
(2008-08-22)
Classical Hodgkin lymphoma (cHL) is a malignant disorder with striking
inflammatory features. Since cysteinyl leukotrienes (cysLTs) are potent
inflammatory mediators it was of interest to study their potential role
in ...