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Causal inference in epidemiological research
(2009-01-16)
Traditionally, statistics has been viewed as the branch of science which
deals with association. Many epidemiological research questions, however,
are concerned with causation, not association. In this thesis we ...
Oral health in patients with chronic kidney disease
(2009-11-13)
Chronic kidney disease (CKD) is a complex disorder in which active intervention leads to longer survival expectancy. Oral diseases are complex disorders caused mainly by bacterial, fungal, or viral infections, where primary ...
Role of genes and environment for the development of rheumatoid arthritis : results from the Swedish EIRA study
(2009-01-09)
Rheumatoid arthritis (RA) is a complex disease with autoimmune features primarily causing destruction in the joints of the body. Knowledge regarding risk indicators and causes are increasing but so far only a few genetic ...
Optimisation of dengue diagnostic tools in order to increase the knowledge of the pathogenesis
(2008-10-03)
Dengue fever (DF) is the most common global viral mosquito-borne infection, with 100 million estimated cases annually in tropical and subtropical areas. The dengue viruses (genus Flavivirus, Flaviviridae) occur in 4 serotypes ...
Tissue biomarkers in prostate cancer
(2009-09-25)
Prostate cancer (PC) is the most common male cancer in the western world. Better biomarkers are needed to support diagnosis, prediction of prognosis and treatment decision Radical prostatectomy (RP) specimens are routinely ...
Health enhancing physical activity, sociodemographic factors and the neighbourhood environment
(2009-05-05)
groups were observed. The environmental module showed good test-retest reliability, with intra-class correlations ranging from 0.36 regarding questions of a subjective nature to 0.98 for questions of an objective nature, with minor differences...
Population-based studies on familiality and prognosis in patients with monoclonal gammopathies
(2009-05-22)
by computing relative survival ratios (RSRs). One-, 5-, 10-, and 15-year RSRs were 0.98 (95% CI 0.97-0.99), 0.93 (0.91-0.95), 0.82 (0.79-0.84), and 0.70 (0.64-0.76), respectively. Younger age at MGUS diagnosis was associated with a significantly lower excess...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
(n=42 814) were analyzed to assess the association of statin therapy at discharge with one year survival. After multivariable adjustment, statin at discharge was associated with a 37% reduction in one year mortality (HR 0.63, 95% CI 0.58-0.68, p<0...
Intramuscular or periosteal acupuncture for patients with chronic musculoskeletal pain in the neck and low back : effects on pain, physical and psychological functioning
(2008-10-23)
Background: Periosteal acupuncture has shown promising results in the
clinic. No studies of effects in patients with chronic pain in the neck
and low back are today available.
Aims: The main purpose was to compare ...
Diabetes mellitus in patients with coronary artery disease : cardiovascular risk assessment and impact of available treatments
(2008-11-28)
A majority of patients with coronary artery disease have abnormal glucose
regulation and as many as 30% overt diabetes mellitus. Despite
considerable improvements in the management of cardiovascular diseases,
patients ...