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Statin-induced cellular effects mediated by the P2X7 receptor
(2009-05-22)
Cholesterol-lowering statins have been shown to inhibit growth of
different cancer cells both in vitro and in vivo. Epidemiological studies
also indicate a chemopreventive effect of statins. We have investigated
the ...
CD8alpha/alpha+ T-cells and immune memory
(2009-04-29)
TB vaccination and after Mtb infection was further analyzed in Paper IV. CD8αα+ T-cells underwent similar phenotypical changes as observed in the CD4+ and CD8αβ+ T-cell compartments, in vaccinated but not in non-vaccinated animals: loss of IL-7Rα...
Activities with balance limitations among patients with perpheral arthritis : description and assessment
(2008-08-25)
Background and aim: Patients with peripheral arthritis (PA) have several
impairments that can influence balance and be risk factors for falls and
fear of falling. Since disability varies among these patients, we need ...
Heart rate variability in patients with stable angina pectoris
(2009-01-16)
The rate and modulation of the heart beat (i.e. heart rate variability; HRV) are controlled by the autonomic nervous system. Cardiac sympathetic activation decreases and parasympathetic increases HRV. Measurements of HRV ...
Synthetic studies of nitrogen containing heterocycles, particularly pyrazole and benzotriazine derivatives
(2009-11-06)
This thesis will mainly focus on the chemistry of nitrogen containing heterocyclic compounds, particularly pyrazole and benzotriazine and related ring systems to these compounds. The first part includes a short introduction ...
Evaluations of measurement techniques in functional dyspepsia : electrogastrography, satiety drinking test and 14C-urea breath test
(2010-08-20)
The overall aim of this thesis was to evaluate the clinical usefulness of certain measurement techniques that may be helpful in the understanding of functional dyspepsia (FD). Electrogastrography (EGG) parameters were ...
Body and soul : studies on health and psychosomatic complaints among adolescents in Sweden
(2008-10-07)
Objective: The aim of this thesis is to describe the health of the
adolescents with special emphasis on psychosomatic complaints.
Method: Both quantitative and qualitative methods were used to get a
insight into ...
Influence of renal dysfunction on therapy and prognosis in patients with myocardial infarction
(2010-04-30)
The aim of this thesis is to evaluate the influence of renal dysfunction on the presentation for myocardial infarction (MI), its treatment and outcome. Patients between 2003 and 2006 were selected from the nationwide Swedish ...
Peripheral venous catheters : quality of care assessment
(2009-12-31)
About half of the patients admitted to hospitals receive intravenous
therapy through peripheral venous catheters (PVCs). Unfortunately, the
use of PVCs is associated with the risk of complications that may lead to
increased ...
Studies on the phenotype of LXRβ-/- mice : from malabsorption to amyotrophic lateral sclerosis
(2008-10-06)
Liver X Receptors, LXRalpha and LXRbeta (NR1H2) are nuclear receptors
belonging to the superfamily of ligand-activated transcription factors
with a key role in the control of lipid and glucose metabolism. Studies
of the ...