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Statin-induced cellular effects mediated by the P2X7 receptor
(2009-05-22)
Cholesterol-lowering statins have been shown to inhibit growth of
different cancer cells both in vitro and in vivo. Epidemiological studies
also indicate a chemopreventive effect of statins. We have investigated
the ...
Integrated assessment of environmental and human health risks of antibiotic residues and resistance for environmental and health policy
(2021-04-27)
Background: Antibiotic resistance is a global health crisis and a serious threat to progress in achieving the Sustainable Development Goals. This requires a One Health response that recognises the link between human and ...
Therapeutic response in human cancers : the dual role of STAT signalling
(2016-08-08)
STAT proteins were discovered as the mediators of interferon (IFN) signalling in response to viral infections. Later, it has become evident that STATs are activated by many stimuli and that they exert multifaceted effects ...