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Family caregivers of relatives with a life-threatening cancer disease
(2007-05-15)
and development in relational functioning during the first year after the patients diagnosis. In a sample of 91 significant others, data was collected on four occasions. Fifty-two percent of significant others reported change in relational functioning during...
Perceived allergy and hypersensitivity – especially food hypersensitivity – and the consequences for children, adolescents and their families
(2007-10-26)
Background: Allergy and hypersensitivity are growing health issues with impact on the individual’s physical and psychosocial quality of life, work and social life. This thesis focuses on children and adolescents with ...
Predictors of cognitive decline in memory clinic patients
(2007-05-18)
Background: The major challenge in memory clinics is to predict
development as well as non-development of dementia among the
heterogeneous group of patients with cognitive complaints. Since the
advent of pharmacological ...
Studies on natural antisense RNAs and microRNAs
(2007-11-27)
Regulatory RNAs are found in all kingdoms of life and involved in
regulation of gene expression at various steps including RNA splicing,
editing, stability, modification, export, translation and chromatin
remodelling. ...
Physical activity in the severely obese : studies on measurement and promotion
(2007-03-26)
Background: The amount and quality of evidence on how to effectively
promote physical activity (PA) is low compared to what is known about the
health effects of regular PA, especially in obese individuals.
Aim : ...
Transcriptional and post-transcriptional regulation of telomerase reverse transcriptase (hTERT) expression : the role of histone modification and alternative splicing
(2008-01-18)
Telomerase, an RNA-dependent DNA polymerase responsible for telomeric DNA
elongation, is silent in most normal differentiated human cells due to
the tight repression of its catalytic unit, telomerase reverse
transcriptase ...
Transcriptional regulation by inner nuclear membrane proteins
(2007-04-19)
, bind promoters of SPS-sensor regulated genes and induce their transcription. Recessive loss-of-function mutations in ASI1, ASI2 and ASI3 (amino acid sensor independent) genes bypass the requirement of a functional SPS-sensor and constitutively induce...
Swedish moist snuff and the risk of cardiovascular diseases
(2007-10-19)
The snuff consumption in Sweden has increased substantially during recent
decades and today more than every fifth male adult uses snuff daily.
However, the evidence on health effects from long-term use of snuff is
limited, ...
Toxicological studies of opiate-related death
(2007-04-25)
This thesis comprises studies on opiate overdose death, and focuses on
evaluation of toxicological characteristics including the possible
influence of abstinence and polydrug use for the fatal outcome.
In order to ...
The impact of airway-irritating exposure and wet work on subjects with allergy or other sensitivity : epidemiology and mechanisms
(2007-09-14)
The prevalence of asthma and allergies is increasing, which means that
the proportion of workers on the labour market with allergy or other
sensitivity also increases. It is as of yet not known to what extent
these ...