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Analytical and pharmacological studies of cyclophosphamide
(2008-03-17)
-liquid extraction (LLE) and analyzed using liquid chromatography with UV detection (LC-UV). The limit of detection (LOD) was 0.005 μg/mL and the limit of quantification was 0.5 μg/mL for LC-MS/MS. The accuracy of the quality control (QC) samples ranged from 91...
Caesarean section on maternal request : personality, fear of childbirth and signs of depression among first-time mothers
(2007-05-15)
Aim: The overall aim of this thesis was to study healthy first-time mothers
requesting and undergoing an elective caesarean section (CS) and to
compare these to healthy first-time mothers planning a vaginal delivery.
The ...
Psychological health and life situation in spouses of stroke patients
(2007-05-25)
About 30,000 people in Sweden are affected by stroke each year. The
effect on physical functioning, and also consequences such as depression
and aphasia, are likely to affect not only the life of the patient, but
also the ...
Psychosocial work conditions and musculoskeletal complaint : the role of affective stress response as a mediator of the effect of psychosocial risk factors on musculoskeletal complaints
(2007-11-22)
The hypothesis tested in these two studies was that unfavourable
psychosocial work conditions are expected to increase the risk of
musculoskeletal complaints (MSC), and that this effect is at least partly
mediated by ...
Induction and repair of DNA double-strand breaks in human cells exposed to different radiation qualities
(2008-02-22)
Radiation therapy is used in attempting to kill tumor cells by inducing DNA double- strand breaks (DSB), the most critical DNA lesions. Recent and planned radiation therapy strategies use high-linear energy transfer (LET) ...
Asthenopia in schoolchildren
(2007-05-11)
Asthenopia is a term used to describe different symptoms associated with the use of the eyes, such as pain, blurred vision, diplopia, headaches. Asthenopia is most often reported in association with near vision. Children ...
Induction of human cytochrome P450 enzymes : predictive in vitro models and rifampicin induction in vivo
(2008-01-24)
The cytochrome P450 (P450) enzymes comprise the most important enzyme
system with regard to phase I metabolism of drugs. Induction of P450s can
result in decreased plasma concentrations of the drug itself or a
coadminstered ...
Cell transplantation with human mesenchymal or embryonic stem cells to the heart : experimental, molecular, immunological and echocardiographic studies
(2007-11-16)
Background: Human mesenchymal stem cells (hMSC), human embryonic stem
cells (HESC) and human fetal cardiomyocyte progenitor cells (HFCP) all
represent possible candidate cells for regeneration of damaged
myocardium. ...
Role of membrane associated molecules in liver fibrosis
(2008-03-07)
The aim of the study was to evaluate the role of membrane associated proteins in tissue formation and remodeling, in normal embryogenesis and in liver disease. Molecules associated with cellular membranes provide a ...
Hyperthyroidism : incidence and long term quality-of-life
(2008-03-07)
Hyperthyroidism is a common disorder which in general affects
approximately 2 % of women and 0.2 % of men. There are three main types
of hyperthyroidism, caused by increased thyroid hormone production:
Graves disease, ...