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Human cytomegalovirus (HCMV) infection in patients with inflammatory bowel diseases (IBD) : role in pathogenesis and autoimmunity
(2004-11-19)
Human cytomegalovirus (HCMV) is one of eight members of the herpesvirus
family that infects humans. Like other herpes viruses, HCMV establishes a
latent infection after the primary infection, and reactivation may ...
The family triad : the interaction between the child, its mother, and father from birth to the age of 4 years old
(2006-10-06)
The aim of this thesis was to describe how early triadic interaction between the newborn child and its mother and father begins, develops, and matures over the child's first 4 years of life. Systemic family theory and ...
Follow-up studies of the obstetrical brachial plexus injury
(2006-09-15)
Aims: The overall aim of these studies were to investigate the influence of different kinds of treatment of the obstetrical brachial plexus lesion, and to study functioning and participation in adolescents with ...
Some lifestyle-related factors and risk of chronic renal failure : a population-based approach
(2005-02-11)
µmol/l (men) or 250 µmol/l (women) during the two-year study period, 1996-1998. The final study population included 926 cases and 998 randomly selected controls from the study base. A face-to-face interview and a self-administered questionnaire provided...
Nitric oxide and evaluation of different treatments in experimental colitis and inflammatory bowel disease
(2006-11-10)
Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn's disease (CD), is a chronic inflammatory disorder of unknown etiology of the gastrointestinal tract. Central features of IBD are increased ...
Regulation of signal transduction in the striatum by typical and atypical antipsychotic drugs
(2005-05-13)
The only effective therapy for schizophrenia is based on the use of antipsychotic drugs. These substances act as dopamine D 2 receptor antagonists and can be classified as typical or atypical. Typical antipsychotics, e.g. haloperidol, reduce...
In vivo quantification of extrastriatal dopamine D2 receptors in the human brain
(2005-03-25)
The dopamine D2 receptor subtype attracts considerable attention in research on the patophysiology and drug treatment of several neuropsychiatric disorders, such as schizophrenia and Parkinson's disease. The brain imaging technology Positron...
The role of Nkx proteins neuronal and glial specification
(2004-11-12)
) are sequentially generated from a domain defined by the expression of Olig2. We show that the generation of sMNs and OLPs in the ventral spinal cord is essentially missing in mice lacking Nkx6 function. In contrast, the same HD proteins instead act to suppress OLP...
Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population
(2006-11-10)
The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and ...