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Studies on the regulation of human skeletal muscle lipolysis in vivo
(2004-11-12)
Intramuscular triglyceride deposits are a significant energy source, and are considered to be of importance in the pathogenesis of skeletal muscle insulin resistance. In contrast to adipose tissue, the lipolytic process ...
Metacarpophalangeal pattern profile analysis in hypochondroplasia, dyschondrosteosis and Turner syndrome
(2004-10-22)
The skeletal system, including the hand skeleton, is affected by a large number of skeletal dysplasias. Clinical and radiological abnormalities of the skeletal system in hypochondroplasia (HCP), dyschondrosteosis (LWD) and ...
The metabolic syndrome : studies on thrifty genes
(2004-09-25)
and their dysfunction might be associated with increased
muscle lipid accumulation and insulin resistance. The relative
contribution of the two glucose transport proteins GLUT1 and GLUT4 was
studied by using a novel photolabeling technique in primary cultures of
human...
Hormonal mechanisms of menstrual disturbances, metabolic disorders and effects of oral contraceptives in female athletes
(2004-11-12)
Background: During the last decades the number of women participating in sports has increased dramatically. Although exercise has beneficial health effects for most of these women, we now realize that strenuous exercise ...
Viridans group streptococci septicaemia and endocarditis : molecular diagnostics, antibiotic susceptibility and cinical aspects
(2005-04-27)
Viridans group streptococci (VGS) are inhabitants in the oral cavity and in the gastrointestinal tract. They cause severe infections, they are responsible for up to 39 % of the cases of septicaemia in neutropenic patients ...
Characterization of ERp29 : a novel secretion factor of endoplasmic reticulum
(2005-04-29)
ERp29 is a ubiquitously expressed endoplasmic reticulum protein strongly
conserved in mammalian species. The N-terminal domain of ERp29 is similar
to the thioredoxin domain of protein disulfide isomerase (PDI) lacking
however ...
Nephrin-mutations in congenital nephrotic syndrome of the Finnish type and cell lineage specific gene regulation
(2005-04-21)
of kidney and brain specific regulatory elements in the region -4 kb; -2.1 kb (where the first nucleotide of the ATG codon of nephrin is +1). The sequence between -1.9 and -1.2 kb was found to be important for spinal cord and pancreas expression...
Novel methods for the identification of cellular S-glutathionylated proteins and sites of glutathionedependent modification using affinity chromatography and proteomic analyses
(2005-02-21)
Reactive oxygen species (ROS) are formed during normal respiration in the mitochondria through electron leakage to oxygen. During normal metabolism, several enzymes and low-molecular weight antioxidants work towards ...
Molecular genetic studies of psoriasis susceptibility in 6p21.3
(2005-02-18)
, the genetic contribution to the disease is strong. Several loci have been identified and among these, psoriasis susceptibility 1 (PSORS1) in chromosome region 6p21.3 is consistently described in populations of different ethnic background. A major factor...
Dietary and genetic factors in the etiology of prostate cancer
(2006-05-19)
The etiology of prostate cancer is poorly understood. However, genetic factors may be more important than for many other malignancies. In addition, several studies suggest that dietary factors axe of etiologic importance. ...