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Studies on fibronectin binding proteins, proteases, and virulence in Staphylococcus aureus
(2004-11-12)
significantly potentiated S. aureus infection in mouse gastrocnemius muscle. Acute muscle damage caused by the myotoxic phospholipase A2 MTIII and ECM degradation by endogenous matrix metalloproteinases (MMP-2 and MMP-9) seemed to be the most important factors...
Myasthenia gravis : clinical aspects and possible involvement of prolactin
(2006-09-15)
controls. The levels of plasma PRL were raised in 101 women with MG, but not in 91 men. There was an association between high prolactin levels and high levels of autoantibodies against the AChR. There was no association between PRL levels and thymic...
Synthetic studies of marine indole alkaloids and related systems
(2005-11-25)
and 8,9dihydrobarettin, isolated from the marine sponge Geodia baretti. The synthesis of barettin and 8,9dihydrobarettin was performed in this work, involving a highly functionalised arginine derivative. This arginine derivative was used in a peptide...
Risk factors for haematological malignancies : immune-mediated diseases, body mass index and magnetic fields
(2006-11-03)
model. We found no association between magnetic field exposure and childhood leukaemia overall. However, elevated risk estimates were found in subgroup analyses of acute lymphoblastic leukaemia in the 5-9 year age group. Random variation is a likely...
Cellular and molecular mechanisms in abdominal aortic aneurysm growth and rapture
(2005-11-11)
-degrading proteases in the AAA wall. Gene arrays and quantitative real-time PCR showed that matrix metalloproteinase (MMP)-1, -7, -9 and -12 mRNA expressions were upregulated in the thrombus-free wall compared with the thrombus-covered wall. Immunohistochemistry...
Genetic and immunological control of human myasthenia gravis
(2005-09-23)
Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and ...
The family triad : the interaction between the child, its mother, and father from birth to the age of 4 years old
(2006-10-06)
the child was 3, 9, 18, and 48 months of age. The study is part of an international collaboration to describe the development of triadic interaction in four groups: 20 Swiss German-speaking families, 20 Swiss French-speaking families, 20 American families...
Tobacco smoking and periodontal health in a Saudi Arabian population
(2005-09-23)
Background & Aim: Tobacco smoking exerts a harmful effect on the periodontal tissues manifested by periodontal pockets, attachment loss and periodontal bone loss. Current evidences on the effects of tobacco on periodontal ...
Diabetes, physical activity and endometrial cancer
(2006-11-22)
Accumulating evidence suggests that hyperinsulinemia, in the context of insulin resistance, is associated with carcinogenesis. Physical activity is involved in the regulation of metabolic and hormonal pathways and is an ...