Search
Now showing items 1-10 of 31
Dynamic magnetic resonance imaging of the breast : imaging features for diagnosis and prognosis of breast cancer
(2004-10-29)
The general aim of the present thesis was to identify and study dynamic
contrast-enhanced magnetic resonance imaging (CE-MRI) features that
contribute to the diagnosis and may help in predicting prognosis in
breast ...
Tobacco smoking and periodontal health in a Saudi Arabian population
(2005-09-23)
Background & Aim: Tobacco smoking exerts a harmful effect on the periodontal tissues manifested by periodontal pockets, attachment loss and periodontal bone loss. Current evidences on the effects of tobacco on periodontal ...
Skeletal muscle metabolic flexibility : the roles of AMP-activated protein kinase and calcineurin
(2007-03-23)
Skeletal muscle fibers differ considerably in their metabolic and
physiological properties. The metabolic properties of skeletal muscle
display a high degree of flexibility which adapts to various
physiological demands ...
VEGF-B in islet of langerhans : role in vascular signaling and lipid handling
(2020-02-13)
The discovery of Vascular endothelial growth factor (VEGF)-B’s role in endothelial fatty acid uptake and tissue lipid accumulation opened a new arena for exploration of VEGF-B in lipid metabolism. Indeed, later studies ...
Mechanism of action of antipsychotic drugs : focus on the nucleus accumbens and the prefronta cortex : an experimental study
(2005-05-06)
Antipsychotic drugs have been classified as typical or atypical. To
achieve an effective antipsychotic effect with typical antipsychotic
drugs, e.g. haloperidol, a dopamine D2 receptor blockade of about 70%
seems ...
The post-polio syndrome : studies of immunology and immunomodulatory intervention
(2005-09-02)
Late effects in patients with prior poliomyelitis were first reported in the nineteenth century and have been referred to as the post-polio syndrome (PPS). PPS is characterized by new muscular deterioration, fatigue and ...
Epigenetics in health and disease : on smoking, multiple sclerosis, and rheumatoid arthritis disease states
(2019-10-03)
The main aim of this thesis was to investigate the genome-wide DNA methylation in tissues associated with the immunopathogenesis of two autoimmune diseases, Rheumatoid Arthritis (RA) and Multiple Sclerosis (MS), as well ...
Estrogen and aryl hydrocarbon receptor signaling
(2009-05-22)
The biological effects of estrogens are mediated by the two estrogen receptor (ER) isoforms, ERa and ERb. The ERs are ligand-inducible transcription factors that belong to the nuclear receptor (NR) superfamily. Ligand-activated ...
Role of water channels in kidney and lung
(2009-11-27)
Aquaporins (AQPs) are membrane proteins that function as water channels facilitating a rapid and regulated transport of water across cell membranes. AQPs in kidney and lung play pivotal roles for the regulation of water ...
Intrauterine immunology in allergy and infection
(2009-01-02)
Pregnancy is interesting from an immunological point of view. The maternal immune system has to tolerate the fetus and at the same time also protect against infection. The placenta is not a completely tight barrier: in ...